Neonatal disruption of serine racemase causes schizophrenia-like behavioral abnormalities in adulthood: clinical rescue by d-serine.

BackgroundD-Serine, an endogenous co-agonist of the N-methyl-D-aspartate (NMDA) receptor, is synthesized from L-serine by serine racemase (SRR).Given the role of D-serine in both neurodevelopment and the pathophysiology of schizophrenia, we examined whether neonatal disruption of D-serine synthesis by SRR inhibition could induce behavioral abnormal

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Recovery Technology of Bottom Coal in the Gob-Side Entry of Thick Coal Seam Based on Floor Heave Induced by Narrow Coal Pillar

To improve the resource recovery efficiency of mining face in thick coal seams, the correlation between deformation failure of bottom coal in the gob-side entry and coal pillar width was analyzed by theoretical analysis, numerical calculation, and similar simulation experiments.The results showed that, when the VIBRATOR LAYON coal pillar was strong

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