BackgroundD-Serine, an endogenous co-agonist of the N-methyl-D-aspartate (NMDA) receptor, is synthesized from L-serine by serine racemase (SRR).Given the role of D-serine in both neurodevelopment and the pathophysiology of schizophrenia, we examined whether neonatal disruption of D-serine synthesis by SRR inhibition could induce behavioral abnormal
Do smallholder farmer-led seed systems have the capacity to supply good-quality, fungal-free sorghum seed?
Abstract Local seed systems that are developed, managed and maintained by farmers are a fundamental practice in smallholder crop production, supporting more than 80% of farmers in sub-Saharan Africa and feeding more than 70% of its population.The resilience of such systems is under threat from poverty, climate change, drought, increased pests and d
Recovery Technology of Bottom Coal in the Gob-Side Entry of Thick Coal Seam Based on Floor Heave Induced by Narrow Coal Pillar
To improve the resource recovery efficiency of mining face in thick coal seams, the correlation between deformation failure of bottom coal in the gob-side entry and coal pillar width was analyzed by theoretical analysis, numerical calculation, and similar simulation experiments.The results showed that, when the VIBRATOR LAYON coal pillar was strong
The role of the pressure in the endotracheal tube cuff in the development of iatrogenic tracheal injuries
Background.The endotracheal tube insertion, which is a veritable patient care procedure, carries risks and possible adverse effects.Such complications vary in severity and range from mild symptoms such as sore throat or cough, which are often considered normal post-intubation events, to severe damage, including damage to the vocal cords, trachea, m